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Zero Covid now- Cog reports B117 strain has combined with the Brazilian strain.
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By (user no longer on site) OP
over a year ago
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We were warned this could happen. Sage have been worried about our high virus levels and were worried about not closing our borders but as usual and true to form.... Boris couldn’t make the hard but right choice.
We have become the Petri dish for Covid and emerging strains.
This could be detrimental to our vaccine strategy.
Wait for the shit storm in number 10 tonight.
We need a zero Covid strategy now. |
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By (user no longer on site) OP
over a year ago
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"Oh and, more lockdowns and, more erosion of our liberty."
Versus more deaths and pressure on the NHS.
Nz has had only 11 weeks of lockdown in the past 12 months. How many weeks have we had?
Can expect other countries to shut their borders to us now
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"Oh and, more lockdowns and, more erosion of our liberty.
Versus more deaths and pressure on the NHS.
Nz has had only 11 weeks of lockdown in the past 12 months. How many weeks have we had?
Can expect other countries to shut their borders to us now
"
If we'd done the March lockdown properly we could have a full life minus international travel now.
I'd rather short and sharp than endless in and out. I'm sure it'd be better for the economy too. |
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Things won't get better while companies like mine are still open. 43 sites, 2,500 employees. But because just one of our sites is handling PPE distribution they are all open. My site just handles clothing for a well known supermarket. |
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By (user no longer on site) OP
over a year ago
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"Oh and, more lockdowns and, more erosion of our liberty.
Versus more deaths and pressure on the NHS.
Nz has had only 11 weeks of lockdown in the past 12 months. How many weeks have we had?
Can expect other countries to shut their borders to us now
If we'd done the March lockdown properly we could have a full life minus international travel now.
I'd rather short and sharp than endless in and out. I'm sure it'd be better for the economy too."
Exactly- no more rolling lockdown’s - let this be the last. |
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"The mental health wellbeing will be more of the concern soon if not already "
People have been saying that since the start. As if a huge death toll, grief, endless anxiety about the changes, and the looming mountain of disability from the raging pandemic are not also causes of distress. |
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By (user no longer on site)
over a year ago
|
"We were warned this could happen. Sage have been worried about our high virus levels and were worried about not closing our borders but as usual and true to form.... Boris couldn’t make the hard but right choice.
We have become the Petri dish for Covid and emerging strains.
This could be detrimental to our vaccine strategy.
Wait for the shit storm in number 10 tonight.
We need a zero Covid strategy now."
Was it humans who combined the strains?
Was it humans who made the virus mutate?
Was there a recent new virus strain first found in the UK- not imported? |
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"We were warned this could happen. Sage have been worried about our high virus levels and were worried about not closing our borders but as usual and true to form.... Boris couldn’t make the hard but right choice.
We have become the Petri dish for Covid and emerging strains.
This could be detrimental to our vaccine strategy.
Wait for the shit storm in number 10 tonight.
We need a zero Covid strategy now.
Was it humans who combined the strains?
Was it humans who made the virus mutate?
Was there a recent new virus strain first found in the UK- not imported? "
The more it spreads the more it will mutate. Humans spread it.
I think this also applies to viral recombination but help I need a microbiologist 
I've lost count of how many variants there are now but see above |
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By (user no longer on site)
over a year ago
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"The mental health wellbeing will be more of the concern soon if not already "
This mental health surge that is coming is going to be unprecedented.
Its affecting us two.
Constantly out at work and no way of releasing our stress in our downtime.
All you see everywhere is doom and gloom.
Both had the virus and the Mrs had her vaccine last week.
Me personally a person who has never had any mental health problems I am finding having the virus was a walk in the park compared to my mental state at the moment.
The Mrs stress comes from having death all around her in the first wave.
She works in a nursing home. |
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"Oh and, more lockdowns and, more erosion of our liberty.
Versus more deaths and pressure on the NHS.
Nz has had only 11 weeks of lockdown in the past 12 months. How many weeks have we had?
Can expect other countries to shut their borders to us now
"
Ffs what makes you think we are locked down? Not in anyway are we locked down. Look at the roads? The shops? The wankers loitering around essential coffee shops.... We use words and get suckered into believing them. |
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"Oh and, more lockdowns and, more erosion of our liberty.
Versus more deaths and pressure on the NHS.
Nz has had only 11 weeks of lockdown in the past 12 months. How many weeks have we had?
Can expect other countries to shut their borders to us now
Ffs what makes you think we are locked down? Not in anyway are we locked down. Look at the roads? The shops? The wankers loitering around essential coffee shops.... We use words and get suckered into believing them. "
Agreed.
I'm on a personal lockdown. All I can do. It's sad, I'd do more if I could, but the rules are what they are (and compliance is what it is). I take personal responsibility. |
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"We were warned this could happen. Sage have been worried about our high virus levels and were worried about not closing our borders but as usual and true to form.... Boris couldn’t make the hard but right choice.
We have become the Petri dish for Covid and emerging strains.
This could be detrimental to our vaccine strategy.
Wait for the shit storm in number 10 tonight.
We need a zero Covid strategy now.
Was it humans who combined the strains?
Was it humans who made the virus mutate?
Was there a recent new virus strain first found in the UK- not imported? "
It didn't combine it, the uk one naturally mutated to be very similar to the Brazil one, the same PHE think as it has done to resemble the sa strain |
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By *D835Man
over a year ago
London |
"The mental health wellbeing will be more of the concern soon if not already
People have been saying that since the start. As if a huge death toll, grief, endless anxiety about the changes, and the looming mountain of disability from the raging pandemic are not also causes of distress."
true  |
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"We were warned this could happen. Sage have been worried about our high virus levels and were worried about not closing our borders but as usual and true to form.... Boris couldn’t make the hard but right choice.
We have become the Petri dish for Covid and emerging strains.
This could be detrimental to our vaccine strategy.
Wait for the shit storm in number 10 tonight.
We need a zero Covid strategy now.
Was it humans who combined the strains?
Was it humans who made the virus mutate?
Was there a recent new virus strain first found in the UK- not imported?
The more it spreads the more it will mutate. Humans spread it.
I think this also applies to viral recombination but help I need a microbiologist
I've lost count of how many variants there are now but see above "
There's hundreds of known mutations when compared to the original virus sequenced in China in Dec 2019. What's the rest of the question? |
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"We were warned this could happen. Sage have been worried about our high virus levels and were worried about not closing our borders but as usual and true to form.... Boris couldn’t make the hard but right choice.
We have become the Petri dish for Covid and emerging strains.
This could be detrimental to our vaccine strategy.
Wait for the shit storm in number 10 tonight.
We need a zero Covid strategy now.
Was it humans who combined the strains?
Was it humans who made the virus mutate?
Was there a recent new virus strain first found in the UK- not imported?
The more it spreads the more it will mutate. Humans spread it.
I think this also applies to viral recombination but help I need a microbiologist
I've lost count of how many variants there are now but see above
There's hundreds of known mutations when compared to the original virus sequenced in China in Dec 2019. What's the rest of the question?"
Did humans make the virus mutate/combine?
I think one yes, because it doesn't mutate without hosts.
Two, does this involve recombination (Swing is deep in the s - sort of family tree multiple parents ish?) and presumably humans also did this, if it was done, because the virus requires hosts (with lots of hosts more opportunities)? (Is recombination the thing here? Help I'm lost, haha) |
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"Viruses dont "combine" or breed they replicate "
"Viral recombination occurs when viruses of two different parent strains coinfect the same host cell and interact during replication to generate virus progeny that have some genes from both parents."
Fleischmann WR Jr. Viral Genetics. In: Baron S, editor. Medical Microbiology. 4th edition. Galveston (TX): University of Texas Medical Branch at Galveston; 1996. Chapter 43.
(Can be googled, don't know if I'm allowed to link) |
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"Oh and, more lockdowns and, more erosion of our liberty.
Versus more deaths and pressure on the NHS.
Nz has had only 11 weeks of lockdown in the past 12 months. How many weeks have we had?
Can expect other countries to shut their borders to us now
Ffs what makes you think we are locked down? Not in anyway are we locked down. Look at the roads? The shops? The wankers loitering around essential coffee shops.... We use words and get suckered into believing them.
Agreed.
I'm on a personal lockdown. All I can do. It's sad, I'd do more if I could, but the rules are what they are (and compliance is what it is). I take personal responsibility."
Yes me to, the difference is I'm seeing patients. I can see the masses but, will be reported for driving to the beach ! |
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"Oh and, more lockdowns and, more erosion of our liberty."
Get a grip ffs. Erosion of your liberty don't make me laugh. I'll be happy to bet you're an anti vaxxer too aren't you. Deal with what's needed to get out of this and you and your merry band can go back to your conspiracy theories. |
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"Viruses dont "combine" or breed they replicate
"Viral recombination occurs when viruses of two different parent strains coinfect the same host cell and interact during replication to generate virus progeny that have some genes from both parents."
Fleischmann WR Jr. Viral Genetics. In: Baron S, editor. Medical Microbiology. 4th edition. Galveston (TX): University of Texas Medical Branch at Galveston; 1996. Chapter 43.
(Can be googled, don't know if I'm allowed to link)"
A quickie on recombination events in the evolution of the SARS-CoV-2 virus:
Zhu, Z., Meng, K. & Meng, G. Genomic recombination events may reveal the evolution of coronavirus and the origin of SARS-CoV-2. Sci Rep 10, 21617 (2020). https://doi.org/10.1038/s41598-020-78703-6 |
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The greatest the volume of people infected, the higher the volume of mutations that will get created and ultimately follow evolutionary principles, with adaptive benefits over predecessors. Sure, ee can get new variants entering the country but we have had such high levels of infection here that new adaptive elements are able to acccumulate, potentially from earlier variants' adaptive mutations. |
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"Viruses dont "combine" or breed they replicate
"Viral recombination occurs when viruses of two different parent strains coinfect the same host cell and interact during replication to generate virus progeny that have some genes from both parents."
Fleischmann WR Jr. Viral Genetics. In: Baron S, editor. Medical Microbiology. 4th edition. Galveston (TX): University of Texas Medical Branch at Galveston; 1996. Chapter 43.
(Can be googled, don't know if I'm allowed to link)
A quickie on recombination events in the evolution of the SARS-CoV-2 virus:
Zhu, Z., Meng, K. & Meng, G. Genomic recombination events may reveal the evolution of coronavirus and the origin of SARS-CoV-2. Sci Rep 10, 21617 (2020). https://doi.org/10.1038/s41598-020-78703-6"
I googled viral recombination and clicked the first legit link 
But question about role of recombination above. Am I completely off? |
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"Viruses dont "combine" or breed they replicate
"Viral recombination occurs when viruses of two different parent strains coinfect the same host cell and interact during replication to generate virus progeny that have some genes from both parents."
Fleischmann WR Jr. Viral Genetics. In: Baron S, editor. Medical Microbiology. 4th edition. Galveston (TX): University of Texas Medical Branch at Galveston; 1996. Chapter 43.
(Can be googled, don't know if I'm allowed to link)
A quickie on recombination events in the evolution of the SARS-CoV-2 virus:
Zhu, Z., Meng, K. & Meng, G. Genomic recombination events may reveal the evolution of coronavirus and the origin of SARS-CoV-2. Sci Rep 10, 21617 (2020). https://doi.org/10.1038/s41598-020-78703-6
I googled viral recombination and clicked the first legit link
But question about role of recombination above. Am I completely off?"
You have defined viral recombination, yes. It's relatively common in RNA viruses. |
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"
You have defined viral recombination, yes. It's relatively common in RNA viruses."
(Different quote - Was it humans who combined the strains?
Was it humans who made the virus mutate?)
I think the answer is yes. One, chances to spread means chances to mutate. And two, ditto on recombination (but with mixing of variants). Is that right? |
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By (user no longer on site)
over a year ago
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"Oh and, more lockdowns and, more erosion of our liberty."
I haven't seen any real proper lockdown implemented in any of this pandemic here in the UK yet. |
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"
You have defined viral recombination, yes. It's relatively common in RNA viruses.
(Different quote - Was it humans who combined the strains?
Was it humans who made the virus mutate?)
I think the answer is yes. One, chances to spread means chances to mutate. And two, ditto on recombination (but with mixing of variants). Is that right?"
Kind of. It's not DELIBERATE human manipulation (eg in a lab), as some seem to suggest. Being a viral incubator means you do potentially contribute to mutations, yes. The most obvious point for recombination though is where the virus jumps species or acquires multiple new mutations in a short time. |
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"
You have defined viral recombination, yes. It's relatively common in RNA viruses.
(Different quote - Was it humans who combined the strains?
Was it humans who made the virus mutate?)
I think the answer is yes. One, chances to spread means chances to mutate. And two, ditto on recombination (but with mixing of variants). Is that right?
Kind of. It's not DELIBERATE human manipulation (eg in a lab), as some seem to suggest. Being a viral incubator means you do potentially contribute to mutations, yes. The most obvious point for recombination though is where the virus jumps species or acquires multiple new mutations in a short time."
Thank you.
And yeah, I don't mean doing it deliberately. I more mean by not keeping our germs to ourselves Or global travel |
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By (user no longer on site)
over a year ago
|
"
You have defined viral recombination, yes. It's relatively common in RNA viruses.
(Different quote - Was it humans who combined the strains?
Was it humans who made the virus mutate?)
I think the answer is yes. One, chances to spread means chances to mutate. And two, ditto on recombination (but with mixing of variants). Is that right?
Kind of. It's not DELIBERATE human manipulation (eg in a lab), as some seem to suggest. Being a viral incubator means you do potentially contribute to mutations, yes. The most obvious point for recombination though is where the virus jumps species or acquires multiple new mutations in a short time."
I guess this is all pretty much standard virus behaviour thats well known about, that wouldn't surprise a scientist much or cause great alarm? |
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"
You have defined viral recombination, yes. It's relatively common in RNA viruses.
(Different quote - Was it humans who combined the strains?
Was it humans who made the virus mutate?)
I think the answer is yes. One, chances to spread means chances to mutate. And two, ditto on recombination (but with mixing of variants). Is that right?
Kind of. It's not DELIBERATE human manipulation (eg in a lab), as some seem to suggest. Being a viral incubator means you do potentially contribute to mutations, yes. The most obvious point for recombination though is where the virus jumps species or acquires multiple new mutations in a short time.
I guess this is all pretty much standard virus behaviour thats well known about, that wouldn't surprise a scientist much or cause great alarm? "
Yes, pretty standard stuff and basic virology. |
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By (user no longer on site)
over a year ago
|
"
You have defined viral recombination, yes. It's relatively common in RNA viruses.
(Different quote - Was it humans who combined the strains?
Was it humans who made the virus mutate?)
I think the answer is yes. One, chances to spread means chances to mutate. And two, ditto on recombination (but with mixing of variants). Is that right?
Kind of. It's not DELIBERATE human manipulation (eg in a lab), as some seem to suggest. Being a viral incubator means you do potentially contribute to mutations, yes. The most obvious point for recombination though is where the virus jumps species or acquires multiple new mutations in a short time.
I guess this is all pretty much standard virus behaviour thats well known about, that wouldn't surprise a scientist much or cause great alarm?
Yes, pretty standard stuff and basic virology."
Good O. I shall continue to be un alarmed aswell then |
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"
You have defined viral recombination, yes. It's relatively common in RNA viruses.
(Different quote - Was it humans who combined the strains?
Was it humans who made the virus mutate?)
I think the answer is yes. One, chances to spread means chances to mutate. And two, ditto on recombination (but with mixing of variants). Is that right?
Kind of. It's not DELIBERATE human manipulation (eg in a lab), as some seem to suggest. Being a viral incubator means you do potentially contribute to mutations, yes. The most obvious point for recombination though is where the virus jumps species or acquires multiple new mutations in a short time.
I guess this is all pretty much standard virus behaviour thats well known about, that wouldn't surprise a scientist much or cause great alarm?
Yes, pretty standard stuff and basic virology.
Good O. I shall continue to be un alarmed aswell then "
There's no point stressing about mutations because so long as the virus infects people or animals, it will mutate. We SHOULD be concerned about the nature of the mutations and how they might affect the way in which it causes disease and whether the vaccines will need amending and to what extent those already vaccinated would be protected. |
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By *omino51Man
over a year ago
loughborough |
Ive had quite a good year.... trying to say all is not doom and gloom, but im sure i will now get haters for being a happy chappy, during these times. Sum folk just love to moan... love and kisses to all xx |
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"Vaccines don't combine, what has actually happened is that similar mutations have occurred with the British variants of the virus too the ones seen in Brazil an SA
Cal"
... Viral recombination is a thing, see above. |
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"Vaccines don't combine, what has actually happened is that similar mutations have occurred with the British variants of the virus too the ones seen in Brazil an SA
Cal
... Viral recombination is a thing, see above."
I stand corrected, I've never heard that before...
All reports I have seen so far suggest that the UK variants of the virus have "Mutated to resemble" the Brazilian & South Africa mutations.
Cal |
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"Vaccines don't combine, what has actually happened is that similar mutations have occurred with the British variants of the virus too the ones seen in Brazil an SA
Cal
... Viral recombination is a thing, see above.
I stand corrected, I've never heard that before...
All reports I have seen so far suggest that the UK variants of the virus have "Mutated to resemble" the Brazilian & South Africa mutations.
Cal"
Neither had I before I started to listen to virology podcasts 
I don't know if it's recombination, I guess it's possible |
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By (user no longer on site) OP
over a year ago
|
"We were warned this could happen. Sage have been worried about our high virus levels and were worried about not closing our borders but as usual and true to form.... Boris couldn’t make the hard but right choice.
We have become the Petri dish for Covid and emerging strains.
This could be detrimental to our vaccine strategy.
Wait for the shit storm in number 10 tonight.
We need a zero Covid strategy now.
Was it humans who combined the strains?
Was it humans who made the virus mutate?
Was there a recent new virus strain first found in the UK- not imported?
It didn't combine it, the uk one naturally mutated to be very similar to the Brazil one, the same PHE think as it has done to resemble the sa strain"
Agree , it has acquired mutation that the SA and BR strains has- it is still worrying though as over time the risk of vaccine escape increases |
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By (user no longer on site) OP
over a year ago
|
"We were warned this could happen. Sage have been worried about our high virus levels and were worried about not closing our borders but as usual and true to form.... Boris couldn’t make the hard but right choice.
We have become the Petri dish for Covid and emerging strains.
These particular mutations are associated with potential reduced Antibody response..... essential if these mutations keep occurring over time - the risk of vaccine escape increases
This could be detrimental to our vaccine strategy.
Wait for the shit storm in number 10 tonight.
We need a zero Covid strategy now.
Was it humans who combined the strains?
Was it humans who made the virus mutate?
Was there a recent new virus strain first found in the UK- not imported?
The more it spreads the more it will mutate. Humans spread it.
I think this also applies to viral recombination but help I need a microbiologist
I've lost count of how many variants there are now but see above
There's hundreds of known mutations when compared to the original virus sequenced in China in Dec 2019. What's the rest of the question?"
|
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"Vaccines don't combine, what has actually happened is that similar mutations have occurred with the British variants of the virus too the ones seen in Brazil an SA
Cal
... Viral recombination is a thing, see above.
I stand corrected, I've never heard that before...
All reports I have seen so far suggest that the UK variants of the virus have "Mutated to resemble" the Brazilian & South Africa mutations.
Cal"
That's all that I've seen so far, upon the new similar mutations inside the UK. Usually they are able to track the lineage of a specific variant, pinpointing its history.
The quicker that we get to have our infection numbers plummet, the sooner we will be limiting the chances for any strains here to mutate. |
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"Vaccines don't combine, what has actually happened is that similar mutations have occurred with the British variants of the virus too the ones seen in Brazil an SA
Cal
... Viral recombination is a thing, see above.
I stand corrected, I've never heard that before...
All reports I have seen so far suggest that the UK variants of the virus have "Mutated to resemble" the Brazilian & South Africa mutations.
Cal
That's all that I've seen so far, upon the new similar mutations inside the UK. Usually they are able to track the lineage of a specific variant, pinpointing its history.
The quicker that we get to have our infection numbers plummet, the sooner we will be limiting the chances for any strains here to mutate. "
|
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By (user no longer on site)
over a year ago
|
A couple of interesting programmes on BBC2 using 'catchup' 54 Days: China and the Pandemic and then 54 Days: America and the Pandemic.
It's a real eye opener ! |
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By (user no longer on site) OP
over a year ago
|
"Vaccines don't combine, what has actually happened is that similar mutations have occurred with the British variants of the virus too the ones seen in Brazil an SA
Cal
... Viral recombination is a thing, see above.
I stand corrected, I've never heard that before...
All reports I have seen so far suggest that the UK variants of the virus have "Mutated to resemble" the Brazilian & South Africa mutations.
Cal
That's all that I've seen so far, upon the new similar mutations inside the UK. Usually they are able to track the lineage of a specific variant, pinpointing its history.
The quicker that we get to have our infection numbers plummet, the sooner we will be limiting the chances for any strains here to mutate. "
Completely agree,
Numbers should get low by the end of March- it’s what happens then is the key- unlock to quickly and numbers will jump again. |
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