London has several great clubs as has Manchester, Blackpool has a couple as well that are well worth the effort. Between flights and hotels, it's as cheap as a weekend in Ireland.
Been to Birmingham, Manchester and Leeds.had a brilliant time at all.
Chameleons
Cupids
Pandora.
Check out what's on before you go as they maybe having event nights. Check out if they have a bar or is it bring your own..