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Length of protection of vaccine
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From the European Medicines Agency FAQs on the vaccine:
How long will immunity from a vaccine last?
Currently, because the virus is so novel, there is not enough knowledge on how long the immunity conferred by the vaccines will last after vaccination, or whether there will be a need for periodic booster doses.
Data from immunogenicity and efficacy studies in the long term will inform future vaccination strategies. |
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By *asIsaCouple
over a year ago
harrow |
"The "experts" have said anything from 3 onto upwards. The two doses will increase the length of protection "probably" to many years.
Cal"
Not what Chris Witty said at all at the briefing last week. He said they think a minimum of 4 months, max 12 months but we don't know. We will have to wait and see |
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This vaccine is at least 6-8 months behind the data we've got on natural immunity data so it's simply a case of watch this space but 3-4 months seems a safe bet at the moment for the vaccine. I think we're at 8-9 months immunity post infection (for the vast majority of cases) |
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After such a horrible year, we'd all like some certainty of course. The short answer, after just a few months of vaccine trials, is that, I don't think they're very clear on it. They'll continue to monitor it and run tests. Just measuring antibodies' levels would just give us part of the story as our body's immune system is based on a complex web of different systems that each have different roles. Attempting to measure them all is complex and time consuming, particularly compared with antibody levels. We even produce autoantibodies, that have functions that can include destruction of our organs, heart, kidneys, brain, lungs etc. It's thought this autoantibodies attack may be fuelling long covid, long after the virus has gone. |
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And breathe. I should have added some breaks there.
They're assuming repeat boosters will potentially be needed. A mixed treatment of 2 different vaccines may sustain longer immunity but they will research that next year |
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At present, it's an unknown and will probably depend on the type of vaccine used (manufacturer amd method) and the age of the individual being vaccinated (immune response tends to decline with age).
Bear in mind that some vaccines provide long term immunity (e.g. Yellow Fever), some require a primary course of vaccination (e.g. Tetanus (childhood; 3 doses one month apart) before long term interval vaccination 10 years.
Some vaccines require regular short term vaccination for affected areas e.g. Cholera (6 months).
Influenza requires an annual vaccine determined by the strains of the influenza virus predicted to be circulating in the next influenza 'season' due to antigenic drift that subtly alters the characteristics of the virus (infectivity, morbidity and mortality). Antigenic shift is already seen in SARS-CoV-2.
Antigenic shift in influenza (a major change in the characteristics of the virus or SARS-CoV-2 equating to, effectively a novel virus)) will probably require a completely different vaccine.
Finally, the risk of side effects (including serious neurological and fatal anaphylaxis) tends to increase with the number of 'booster' vaccines administered e.g. Yellow Fever.
SS |
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"Hi, apologies if already been posted.
But the covid vaccines, do they off life long protection or is it a yearly injection like the flu vaccine?"
Both Pfizer and Moderna’s trials tested whether their vaccines prevented their participants from getting sick, not whether it prevented them from being infected and potentially passing on the virus to others.
“Would the vaccinated people be similar to that 40 percent of people who have an asymptomatic infection?” Viscidi wondered. “It’s not something they have an answer to right now.” |
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"
Finally, the risk of side effects (including serious neurological and fatal anaphylaxis) tends to increase with the number of 'booster' vaccines administered e.g. Yellow Fever.
"
Yellow Fever no longer needs a booster after ten years. It apparantly lasts forever |
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By *arry247Couple
over a year ago
Wakefield |
"The "experts" have said anything from 3 onto upwards.
So how long is this ?
Sorry that was 3 months upwards..."
The truth is nobody knows yet.
Antibodies have been found in the blood of those previously infected and in some people who have been vaccinated after 3 moths but it is not known whether they give protection.
This is one of those questions we will not really find the answer to for at least a year and possibly even longer but it is hoped the protection will last at least a year. |
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"The "experts" have said anything from 3 onto upwards.
So how long is this ?
Sorry that was 3 months upwards...
The truth is nobody knows yet.
Antibodies have been found in the blood of those previously infected and in some people who have been vaccinated after 3 moths but it is not known whether they give protection.
This is one of those questions we will not really find the answer to for at least a year and possibly even longer but it is hoped the protection will last at least a year."
It has also been suggested that the amount of protection will vary from one person to the next.
Cal |
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"The "experts" have said anything from 3 onto upwards.
So how long is this ?
Sorry that was 3 months upwards...
The truth is nobody knows yet.
Antibodies have been found in the blood of those previously infected and in some people who have been vaccinated after 3 moths but it is not known whether they give protection.
This is one of those questions we will not really find the answer to for at least a year and possibly even longer but it is hoped the protection will last at least a year.
It has also been suggested that the amount of protection will vary from one person to the next.
Cal"
As it does with every single vaccine, because how one responds to a vaccine depends on the individual immune system. |
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"The "experts" have said anything from 3 onto upwards.
So how long is this ?
Sorry that was 3 months upwards...
The truth is nobody knows yet.
Antibodies have been found in the blood of those previously infected and in some people who have been vaccinated after 3 moths but it is not known whether they give protection.
This is one of those questions we will not really find the answer to for at least a year and possibly even longer but it is hoped the protection will last at least a year.
It has also been suggested that the amount of protection will vary from one person to the next.
Cal
As it does with every single vaccine, because how one responds to a vaccine depends on the individual immune system."
What’s more, neither the Pfizer nor the Moderna vaccine trials tested whether the vaccines prevent people from being infected with the virus. Those trials, instead, focused on whether people were shielded from developing disease symptoms. That means that it’s not clear whether vaccinated people could still develop asymptomatic infections — and thus still be able to spread the virus to others.
|
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"The "experts" have said anything from 3 onto upwards.
So how long is this ?
Sorry that was 3 months upwards...
The truth is nobody knows yet.
Antibodies have been found in the blood of those previously infected and in some people who have been vaccinated after 3 moths but it is not known whether they give protection.
This is one of those questions we will not really find the answer to for at least a year and possibly even longer but it is hoped the protection will last at least a year.
It has also been suggested that the amount of protection will vary from one person to the next.
Cal
As it does with every single vaccine, because how one responds to a vaccine depends on the individual immune system.
What’s more, neither the Pfizer nor the Moderna vaccine trials tested whether the vaccines prevent people from being infected with the virus. Those trials, instead, focused on whether people were shielded from developing disease symptoms. That means that it’s not clear whether vaccinated people could still develop asymptomatic infections — and thus still be able to spread the virus to others.
"
Like many other vaccines, such as the whooping cough vaccine. |
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Excuse my ignorance but if its only short term vaccine, and its going to take over a year to vaccine 50% of population how is immunity going happen. By the time they have done the 1st group by end of year they would of lost immunity.
Would only work if 60% were immunised at same time? |
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"The "experts" have said anything from 3 onto upwards. The two doses will increase the length of protection "probably" to many years.
Cal"
I've just declared myself an expert in this matter and I say 187 days if you drink lots of fluids. .... I'm working on a jab to help get replies to emails on fabs next. |
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By (user no longer on site)
over a year ago
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"Excuse my ignorance but if its only short term vaccine, and its going to take over a year to vaccine 50% of population how is immunity going happen. By the time they have done the 1st group by end of year they would of lost immunity.
Would only work if 60% were immunised at same time?"
Yes it will be like painting the Golden Gate Bridge, by the time you get to the end of the vaccination queue, the first ones will need a new vax.
The vaccine is short term and neither stops people catching covid or stops them speading the virus. |
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"Excuse my ignorance but if its only short term vaccine, and its going to take over a year to vaccine 50% of population how is immunity going happen. By the time they have done the 1st group by end of year they would of lost immunity.
Would only work if 60% were immunised at same time?
Yes it will be like painting the Golden Gate Bridge, by the time you get to the end of the vaccination queue, the first ones will need a new vax.
The vaccine is short term and neither stops people catching covid or stops them speading the virus."
You worded it a hell of alot better than me.  |
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By *hagTonightMan
over a year ago
From the land of haribos. |
"The short answer is they don't really know. It could become an annual booster thing but it might give longer lived immunity due to the adjuvants added to boost the immune response."
That is right and just what I was about to say too, noone really know how long it will protect for.
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We don't know how long lived the vaccine immunity is. It might be a year, maybe more. They will continue to follow those immunised in the trials (which started in April) so by April, we'll have data on antibody prevalence after a year. And they'll carry on following them and updating our knowledge base like that for many years, I'd suggest. |
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"Excuse my ignorance but if its only short term vaccine, and its going to take over a year to vaccine 50% of population how is immunity going happen. By the time they have done the 1st group by end of year they would of lost immunity.
Would only work if 60% were immunised at same time?
Yes it will be like painting the Golden Gate Bridge, by the time you get to the end of the vaccination queue, the first ones will need a new vax.
The vaccine is short term and neither stops people catching covid or stops them speading the virus."
But... if enough people are vaccinated and have immunity for just a few weeks, then that is going to be enough for the virus to pretty much die out.
Cal |
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"Nobody knows because it hasn't been properly tested.
Its only taken them less than a year to get this far, how are they going to know how long one dose lasts? "
It's been properly tested. They just don't know how long lived immunity is. It's at least 6 months, seeing as studies commenced in April and data was presented to regulators up to November. |
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